Professor Carlos Caldas

Carlos Caldas is Professor of Cancer Medicine at the University of Cambridge and directs the Breast Cancer Functional Genomics Laboratory at the CRUK Cambridge Institute. He is the Director of the Breast Cancer Programme at the CRUK Cambridge Cancer Centre. His laboratory is focused on characterizing the clonal and cellular heterogeneity of breast cancers and how this affects response to therapy and outcomes, on creating explant models that mimic this heterogeneity and their use for drug testing, and on developing tools to monitor the evolution of breast cancers in space and time.

Carlos’s main contribution to the Grand Challenge will be analysing the unique sample sets accrued in these studies as the primary targets for building 3D tumour maps and how this information will be used as a clinical biomarker