Jordan Squair

Jordan Squair is an MD-PhD–trained Assistant Professor and neurosurgery resident at the University Hospital of Lausanne (CHUV) and NeuroRestore (EPFL–CHUV–UNIL). His work lies at the interface of neurosurgery, genomics, and neuroengineering, with the goal of restoring autonomic and motor function after spinal cord injury and neurodegenerative disease. He has uncovered the spinal mechanisms through which neuromodulation regulates blood pressure and led the development of an implantable neuroprosthetic system that restores cardiovascular stability in people with spinal cord injury. In parallel, his research aims to achieve meaningful nervous system repair by integrating single-cell and spatial transcriptomics, whole-brain and spinal imaging, and neuroprosthetics. Using these approaches, he has identified neuronal subpopulations that are necessary and sufficient for recovery of walking after paralysis and designed targeted repair strategies that restore function even after severe injury. His broader vision is to reframe neurotrauma and neurodegeneration as programmable biological state transitions that can be precisely measured and engineered for repair.