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Pancreatic cancer cell captured with scanning electron microscope

Cancer and the Host

Registration will open on Monday 1 December. If you’re interested in attending, please email events@cancergrandchallenges.org to join the mailing list.

About

Date: Wednesday 17 – Friday 19 June 2026 
Location: The Royal Society, 6-9 Carlton House Terrace, London SW1Y 5AG 

This conference will explore cancer as a systemic disease, emphasising that tumours cannot be understood or treated in isolation. By integrating expertise across disciplines, the conference aims to deepen your understanding of cancer as a host-dependent process and open new frontiers in prevention, treatment, and patient care.

Cancer progressively co-opts and reconfigures immune, metabolic, and neural networks, hijacking normal evolved responses and establishing host-tumour bidirectional interactions that extend far beyond the tumour and its surrounding microenvironment. This systemic interplay shapes disease progression, therapeutic response and patients' outcomes, underscoring the need for approaches that consider the whole individual rather than focusing solely on the tumour.  

Speakers

Marcus DaSilva Goncalves

Marcus DaSilva Goncalves

NYU Langone Health, US

Caroline Dive

Caroline Dive

Cancer Research UK Manchester Institute, UK

James DeGregori

James DeGregori

University of Colorado Anschutz, US

Evangelos Giampazolias

Evangelos Giampazolias

Cancer Research UK Manchester Institute, UK

Tobias Janowitz

Tobias Janowitz

Cold Spring Harbour Laboratory, US

Johanna Joyce

Johanna Joyce

University of Lausanne, CH

Jason Lewis

Jason Lewis

Memorial Sloan Kettering Cancer Center, US

Lydia Lynch

Lydia Lynch

Princeton University, US

Stephen O'Rahilly

Stephen O'Rahilly

University of Cambridge, UK

Erica Sloan

Erica Sloan

Monash University, AU

Claudio Vernieri

Claudio Vernieri

AIRC Institute of Molecular Oncology, IT

Ashani Weeraratna

Ashani Weeraratna

Johns Hopkins University, US

Eileen White

Eileen White

Rutgers Cancer Institute of New Jersey, US

Frank Winkler

Frank Winkler

German Cancer Research Center (DKFZ), DE

Scientific themes

The second edition of the Cancer Grand Challenges Conference Series aims to integrate diverse fields and define the therapeutic value of targeting the host to treat the cancer by bringing together thought leaders from across the cancer research spectrum with experts from immunology through to metabolism and neuroscience.

Cancer does not develop in isolation; it is influenced by the unique biology of its human host. The immune system, metabolic state, microbiome and factors such as aging and stress all shape tumour initiation, growth, metastasis, and therapeutic response. Research on these host-tumour interactions often remain siloed, limiting opportunities to integrate across disciplines. By uniting researchers from across the fields of cancer research and beyond, this conference will serve as a platform to drive innovative experimental approaches, thought-provoking discussions, and translational advances that reflect cancer not only as a disease of cells, but as a systemic host-influenced process.  

Considering cancer as a systemic disease is integral to the approach of Cancer Grand Challenges team CANCAN in tackling the cachexia challenge, and an emerging theme across the Cancer Grand Challenges portfolio.   

Who should attend? 

With only 150 places, this conference is focused on enabling meaningful discussion. It will foster big-picture, interdisciplinary discussions between academic researchers, clinicians and medical professionals, members of the pharmaceutical industry and biotech, as well as funding bodies and policymakers.  It has been designed for the wider scientific community, not just Cancer Grand Challenges funded researchers or those focused on cancer.   

Topics will include: 
 

  • How host physiology influences tumor development and progression 
  • Interactions between cancer and the host immune, metabolic, and neural networks 
  • Strategies to harness host biology for cancer prevention, diagnosis, and treatment  
  • The role of the host environment in shaping therapeutic response 

Programme

Registration, fees and abstracts

Registration 

Registration will open on Monday 1 December 2025 and will close on 1 May 2026. If you’re interested in attending, please email events@cancergrandchallenges.org to join the mailing list. 

Fees 

Registration includes VAT, a light breakfast, networking lunch and coffee breaks on all days, and a welcome reception on Wednesday 17 June. See fees below: 

  • Student/PhD/Postdoc - £150 
  • Academic/Clinical - £300 
  • Industry - £500 

Register via Eventbrite below. Please note that the above prices to not include Eventbrite fees (6.95%, 59p, plus VAT).  

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Abstract submissions 

Abstract submissions will open on Monday 1 December along with registration and close on Friday 20 March 2026. There will be many opportunities for selected talks and poster presentations.  

Abstract evaluation will start after the deadline and may take up to four weeks to complete depending on the number of submissions we receive. Acceptance notifications will go out via email before the end of April 2026. We appreciate your patience.  

Please note that it is not required to submit an abstract to attend the conference. 

Scientific Steering Committee

This conference is being organised by a dedicated steering committee.

Meet the committee members below.

Event information

Get in touch

If you have any questions about this event, please send us an email at events@cancergrandchallenges.org. We'll endeavour to respond to you within two working days.
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Howard Change at Cancer Grand Challenges event
IMAXT team photo

Meet IMAXT, whose challenge was to find a way of mapping tumours at the molecular and cellular level.