Dr Cristina Mayor-Ruiz
Meet Cristina, a co-investigator on PROTECT
Cristina Mayor-Ruiz is a chemical biologist with expertise in targeted protein degradation and proteostasis biology. She is known for mapping the genetic determinants governing the efficiency of degraders, innovating a screening strategy to identify molecular glue degraders, and defining synthetic vulnerabilities to overcome widespread resistance to degraders. Her current research focuses on developing proximity-inducing drugs with therapeutic interest, and on tackling biological questions that involve (dys)regulation of E3 ubiquitin ligases.
Cristina obtained her PhD in 2017 at the CNIO (Madrid), where she unraveled novel mechanisms of resistance to anticancer therapies. In 2018, she joined the group of G. Winter (CeMM, Vienna) for her postdoc and innovated chemical biology approaches in the field of targeted protein degradation. Since January 2021, she is a Group Leader at the Institute for Research in Biomedicine (IRB) in Barcelona. Dr. Mayor-Ruiz has been honored with national and international awards, such as an ERC Starting grant or an Aspire I Award from the Mark Foundation of Cancer Research.